Integrated Drug Discovery and Development Services Our integrated offering allows clients to access multiple outsourcing choices across the research and development value chain. We offer the following servicesAnalytical Services Method Development & Validation Extractables & Leachables Syringability, Injectability, & Inhalation Study Manufacturer Validation Raw Material Qualification ICH Stability & Release Testing Impurity Analysis & Contaminant Identification Pre-Clinical, Clinical, & Post-Approval Pre-Formulation & Formulation Formulation Optimization Solid Stage Characterization IND & NDA Submission Support Counterfeit Analysis Degradation Analysis API Analysis USP Monograph Testing Dissolution Studies Overcoming Solubility Issues Toxicology Analysis Clinical Trial Material Manufacturing Excipient Base Identification Bioequivalence Analysis Disintegration StudiesCustom SynthesisProcess R&DChemistry R&D and Custom SynthesisThe HDH Pharma scientific team has earned its reputation through its problem solving skills and out of the box thinking when coping with challenging chemistry.Reaction OptimizationSynthetic route developmentFeasibility analysis of synthetic pathwaysMethodology studies for process developmentExploratory studies for original compound synthesisCustom Synthesis Services:ImpuritiesBuilding BlocksReference Compounds Reaction IntermediatesPharmaceutical Reference StandardsBuilding blocks and screening compounds Including:4, 5, 6, and 7– membered heterocycles, fused heterocyclesLipids, Carbohydrates, and NucleosidesPyridines, Pyrimidines, Purines, Substituted Benzenes, Pyrazoles, Osoxazoles, Oxadiazoles, Indoles and BenzimidazolesAza-benzimidazoles, and Azitidine, Pyrrolidine, Piperidine