ASCOPHARM is the original CRO structure of the group. ASCOPHARM was founded in early 1995, with an original structure of a non-profit foundation. This was to funnel the message that clinical research was the primary objective of the group and finance was a tool and not an objective. During its last 10 years of existence, several innovative concepts were developed and implemented within the group. Each major innovation motivated the creation of a niche structure. - In late 2002, a holding structure was created, with the name of NOVASCO, in order to integrate financially the different substructures of the group. - Finally, in September 2004, NOVASCO GROUP has signed a master agreement with an Information Service & Data Processing company specialized in the development of clinical research software. Thus, ARONE has integrated NOVASCO Group within that franchise agreement. - Further developments have yet included the signature of an exclusive partnership with an investigational group in oncology (ARCAGY Group GINECO) specialised in the field of female cancers, and creation of a subsidiary based in Dublin, Irl. For International business development (ASCOPHARM Irl. Ltd.). Future developments include negotiation and signature of key other partnerships and international development.